Document 0699
 DOCN  M94A0699
 TI    HIV related Mycobacterium tuberculosis (M.Tb) at Fairfield Hospital.
 DT    9412
 AU    Wright EJ; Sarr A; Dwyer B; Hoy J; Fairfield Hospital, Vic.
 SO    Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:32 (abstract no. FC1).
       Unique Identifier : AIDSLINE ASHM5/94348956
 AB    OBJECTIVE: To review the clinical and laboratory features, management
       and outcome of M.tuberculosis in 18 HIV seropositive patients (2.5% of
       the total AIDS patients). METHODS: A retrospective review of case
       records and laboratory results of 16 male and 2 female patients
       attending Fairfield Hospital between January 1985 and June 1993. The
       median age at presentation was 35 years (25-61 years) and 6 patients
       (33%) had no identifiable risk factors for TB. In 13/18 patients (72%),
       TB was the AIDS defining illness. There was less delay in the diagnosis
       of pulmonary TB than extrapulmonary TB (see table). 4/18 were treated
       presumptively for MAC infection prior to isolation of M.Tb. All isolates
       were fully sensitive to standard TB drugs and treatment was well
       tolerated. 9/18 patients have died and the median survival in the 8/9
       patients diagnosed antemortem was 949 days (R173-1,724 days).
       CONCLUSION: TB occurs in advanced HIV disease, the diagnosis may be
       delayed, treatment is well tolerated and median survival is greater than
       2.5 years. TABULAR DATA, SEE ABSTRACT VOLUME.
 DE    Adult  AIDS-Related Opportunistic Infections/DIAGNOSIS/*EPIDEMIOLOGY
       Cross-Sectional Studies  Female  Human  Incidence  Male  Middle Age
       Retrospective Studies  Tuberculosis, Pulmonary/DIAGNOSIS/*EPIDEMIOLOGY
       Victoria/EPIDEMIOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).