Document 0708 DOCN M94A0708 TI A cavitating lung infection followed by cytomegalovirus polyradiculopathy--discussion of two problems. DT 9412 AU Empson M; Britton W; Garsia R; Department of Clinical Immunology, Royal Prince Alfred Hospital,; Camperdown, NSW. SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:27 (abstract no. TC-4). Unique Identifier : AIDSLINE ASHM5/94348947 AB A 29 year old HIV positive man presented with pleuritic chest pain. haemoptysis and epistaxis. Investigations revealed a cavitating lung lesion, high titre cANCA and scanty pneumocysts. The course was complicated by clinical hypoadrenalism, secondary infection and delirium. CSF obtained to investigate the latter grew CMV after 19 days of incubation. Coinciding with the culture of CMV was the development of micturition difficulty, painful dysaesthesia and weakness of the lower limbs. Ganciclovir was immediately commenced and continued for four weeks at adjusted doses. Despite this, the radiculopathy progressed with the development of a flaccid paraparesis within one week. Recovery was slow but almost complete ten weeks after development of the radiculopathy. The details of the case will be discussed. DE Adult AIDS-Related Opportunistic Infections/*DIAGNOSIS/DRUG THERAPY Case Report Cytomegalovirus Infections/*DIAGNOSIS/DRUG THERAPY Dose-Response Relationship, Drug Drug Administration Schedule Ganciclovir/THERAPEUTIC USE Human Male Meningitis, Viral/*DIAGNOSIS/DRUG THERAPY Neurologic Examination/DRUG EFFECTS Pneumonia, Pneumocystis carinii/*DIAGNOSIS/DRUG THERAPY Polyradiculoneuritis/*DIAGNOSIS/DRUG THERAPY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).