Document 0709 DOCN M94A0709 TI Pneumonitis in association with primary HIV illness. DT 9412 AU Kelly M; Lloyd A; Jones P; Department of Infectious Diseases, Prince Henry Hospital, Little; Bay, Sydney. SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:26 (abstract no. TC-1). Unique Identifier : AIDSLINE ASHM5/94348946 AB A 27 year old homosexual male presented initially with a 5 day illness characterised by fever and rash. Apart from a maculopapular rash there was no physical abnormality. The symptoms resolved spontaneously over a four day period. At presentation P24Ag was positive and then became negative whereas tests for HIV antibody were initially negative and then became positive over a two week period. At presentation the CD4 count was 180 x 10(6)/l and CD8 count was 340 x 10(6)/l. Four weeks after discharge the patient represented with a 7 day febrile illness with dyspnoea and cough. Fine crepitations were heard at the lung bases. The PaO on room air was 73mmHg. The chest x-ray was normal. A bronchoscopy was macroscopically normal. Immunofluorescent studies for Pneumocystis carinii were negative. Bronchoalveolar lavage cell count revealed 60% lymphocytes (73% CD8 and 18% CD4). The peripheral blood CD4 and CD8 cell count were 250 x 10(6)/l and 1190 x 10(6)/l respectively. The patient was commenced on steroids and supplemental oxygen and improved over a three day period. Steroids were subsequently reduced and the patient remained well. Pneumonitis is a rare but significant complication of primary HIV illness which may respond to steroids. DE Adrenal Cortex Hormones/THERAPEUTIC USE Adult Case Report Combined Modality Therapy CD4-CD8 Ratio Diagnosis, Differential Homosexuality Human HIV Seropositivity/*DIAGNOSIS/DRUG THERAPY/IMMUNOLOGY Leukocyte Count Male Oxygen Inhalation Therapy Pneumonia/*DIAGNOSIS/DRUG THERAPY/IMMUNOLOGY T4 Lymphocytes/IMMUNOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).