Document 0935 DOCN M94A0935 TI HIV-1 in patients with sickle cell disease in Zambia. DT 9412 AU Mbewe AL; Dept. of Paediatrics, UTH, Lusaka, Zambia, Africa. SO Int Conf AIDS. 1994 Aug 7-12;10(2):247 (abstract no. PC0350). Unique Identifier : AIDSLINE ICA10/94371640 AB OBJECTIVE: To determine the seroprevalence of HIV-1 in patients with sickle cell disease (HBSS). DESIGN: Cross sectional study. SETTING: Sickle Cell Clinic, University Teaching Hospital, Lusaka, Zambia. PATIENTS: 154 children and adults with sickle cell disease (HBSS). RESULTS: Overall, 22 patients (14%; 95% confidence interval 9 to 19%) were positive for HIV-1 antibodies using the ELISA (Wellcozyme Assay). The relation of the prevalence of HIV-1 positive patients to age group, history of receiving blood transfusion, skin herbal scarification, sex, past medical conditions and current medical conditions is reported. DISCUSSION: The prevalence of HIV-1 in the patients with sickle cell disease (HBSS) was lower than the prevalence in the general population of Zambia. DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS/*EPIDEMIOLOGY Anemia, Sickle Cell/*COMPLICATIONS Cross-Sectional Studies Human HIV Seroprevalence *HIV-1 Zambia/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).