Document 0953 DOCN M94A0953 TI Alcohol-related factors associated with HIV infection among alcoholics. DT 9412 AU Boscarino JA; Avins AL; Woods WJ; Lindan CP; Clark W; Hulley SB; Hudes ES; University of California, San Francisco 94105. SO Int Conf AIDS. 1994 Aug 7-12;10(2):243 (abstract no. PC0335). Unique Identifier : AIDSLINE ICA10/94371622 AB OBJECTIVES: We previously reported alcoholics were at risk for HIV infection (JAMA, 1994; 271:515-518). We now examine if alcohol-related factors predict HIV serostatus among alcoholics entering treatment independent of behavioral risk factors, such as IDU, history of STDs, number of sexual partners, and gay sex. METHODS: Clients entering 2 voluntary residential and 3 outpatient alcoholism treatment centers in the San Francisco area underwent an interview and blind serotesting for HIV antibodies (response rate = 68%). Five alcohol factors (coded as 4-point indicator variables, scored low to high) were used in logistic regressions to predict HIV status: severity of alcoholism at intake, attitudes about socializing in bars, and alcohol expectancies related to risk-taking, enhanced sex, and enhanced self-confidence when drinking. Heterosexual and gay male alcoholics were analyzed separately. RESULTS: A total of 952 subjects entered the study; 76% were males, 16% gay men, 50% African Americans, and 10% Latinos. The overall seroprevalence was 6.3% (95% CI = 4.8-8.0). Among male and female heterosexuals, HIV infection was positively associated with moderate alcoholism severity (OR = 3.3, p = .04) and negatively associated with high risk-taking beliefs (OR = .17, p = .05). Among gay men, HIV infection was positively associated with attitudes about socializing in bars (OR = 13.9, p = .002) and negatively associated with moderate risk-taking beliefs (OR = .07, p = .02). These associations were independent of demographics (gender, education, age, race) and HIV behavioral risk factors (IDU, history of STDs, number of sexual partners, gay sex), and knowledge of current HIV status. CONCLUSION: Among alcoholics, alcoholism severity and attitudes/beliefs about drinking are associated with HIV infection independent of demographic and known behavioral risk factors. Although these associations appear different for gay male and heterosexual alcoholics, our study suggests that it is important to consider different aspects of alcohol abuse as indicators of increased risk of HIV infection. DE Alcoholism/*COMPLICATIONS Ethnic Groups Female Human HIV Infections/*ETIOLOGY Male Risk Factors Risk-Taking Sex Behavior MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).