Document 0955
 DOCN  M94A0955
 TI    Presentation of AIDS in Africans in South London.
 DT    9412
 AU    O'Farrell N; Lau R; Yoganathan K; Pozniak A; Griffin G; Guy's Hospital,
       South London.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):242 (abstract no. PC0329). Unique
       Identifier : AIDSLINE ICA10/94371620
 AB    OBJECTIVE: To ascertain AIDS-defining diagnoses (ADD) in African
       patients attending four South London Hospitals. METHODS: ADD were
       identified from the casenotes to September 1993. CD4 Counts at both HIV
       and AIDS presentations were recorded. RESULTS: The majority 47/62 (76%)
       were from Uganda. Initial ADD were: PCP 14 (23%), TB (pulmonary 4) 12
       (19%), oesophageal candida 8 (13%), cryptococcosis 8 (13%), cerebral
       toxoplasmosis 6 (10%), genital herpes > 1 month 4 (6%), wasting 3 (5%),
       KS 2 (3%), other 5. Subsequent ADD were: cryptococcosis 4, systemic
       mycobacterium avium complex 3, KS 3, others 9. The mean duration of stay
       in the UK prior to HIV diagnosis was < 4 years (mean 1.6 years) in 57 of
       the AIDS cases and 1.3 years in the TB cases. The mean CD4 counts at the
       time of diagnosis of HIV, AIDS and TB were 77, 57 and 111 respectively.
       The initial ADD was the first presentation of HIV infection in 44 (71%).
       CONCLUSIONS: In this population the pattern of ADD showed features
       typical both of AIDS in the West and in Africa. Identification of HIV
       infection was delayed until the onset of AIDS in the majority. Targeting
       of immigrants from areas of high HIV seroprevalence would facilitate
       earlier therapeutic and behavioural interventions.
 DE    Acquired Immunodeficiency Syndrome/*DIAGNOSIS  Africa/ETHNOLOGY
       AIDS-Related Opportunistic Infections/DIAGNOSIS  Human  HIV
       Infections/DIAGNOSIS  London  Uganda/ETHNOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).