Document 0956 DOCN M94A0956 TI Descriptive epidemiology of HIV in Africans in London. DT 9412 AU Low N; Taylor C; Clark R; Pozniak A; Department of Genitourinary Medicine, King's College Hospital,; London, United Kingdom. SO Int Conf AIDS. 1994 Aug 7-12;10(2):242 (abstract no. PC0328). Unique Identifier : AIDSLINE ICA10/94371619 AB INTRODUCTION & METHODS: HIV infection amongst black Africans in the UK has not been extensively studied. Whether there are differences between African patients in Africa and in the UK or between Africans and white patients within the UK is not known. In our centre, black Africans account for approximately 13% of HIV infected patients. We will present the descriptive epidemiology of our cohort whose medical records were reviewed retrospectively. Demographic data and clinical information were recorded and analysed using descriptive methods. RESULTS: Seventy nine patients were identified, of whom 48 were Ugandan. Forty four were female and 35 male, a M:F ratio of 0.79. The mean age of presentation was 29 years for both men and women. Twenty four patients have had 27 AIDS defining illness (ADI), for whom this was the presenting complaint in 13. ADI were oesophageal candida (n = 7), cerebral toxoplasmosis (n = 5), PCP (n = 4), cryptococcal meningitis, TB, wasting, KS (n = 3 each). Presentation with KS occurred at a mean CD4 count of 237, compared with 29 for other ADI combined. COMMENT: The proportion of female patients and their age at presentation is greater than expected, when compared to studies carried out in Africa. African patients present with late stage infection, but less often with PCP than white patients the reasons for which will be explored and presented with an analysis of survival trends and risk factors for progression. DE Adult Africa/ETHNOLOGY AIDS-Related Opportunistic Infections/EPIDEMIOLOGY Female Human HIV Infections/*EPIDEMIOLOGY London/EPIDEMIOLOGY Male MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).