Document 0990
 DOCN  M94A0990
 TI    Adapting GPA guidelines for the clinical management of HIV infection to
       national use. An evaluation of the outcome.
 DT    9412
 AU    Margolis CZ; Wabitsch R; Ben-Gurion University Faculty of Health
       Sciences, Beer-Sheva,; Israel.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):234 (abstract no. PB0950). Unique
       Identifier : AIDSLINE ICA10/94371585
 AB    OBJECTIVES: GPA's guidelines, presented as clinical algorithms, were
       adapted in a standard fashion in a number of countries. This study
       evaluates the extent and the type of differences between the GPA model
       guidelines and two nationally adapted versions. METHODS: Two different
       techniques, the Clinical Algorithms Patient Analysis (CAPA) and Clinical
       Algorithm Nosology (CAN), were used to compare the three sets of
       guidelines. In short the CAN technique translates the clinical logic of
       each individual step between algorithm boxes into a set of If ... then
       conditional statements. These statements serve to pinpoint the
       difference in the logic of the algorithms. The CAPA technique then
       defines a hypothetical patient for each pathway (e.g. chronic
       diarrhoea), analysing the difference in the management advice. RESULTS:
       The analysis shows that the guidelines structure was maintained to a
       large degree (66%). However, patients were managed differently, 83% in
       the area of diagnosis and therapy and 17% related to disease prevalence.
       CONCLUSION: The adaptation process of GPA clinical guidelines preserves
       the original algorithm structure to a large extent but may involve
       significant modifications in the content of clinical care that could
       affect care outcome.
 DE    Algorithms  Comparative Study  Human  HIV Infections/*THERAPY  Practice
       Guidelines/*STANDARDS  World Health Organization  MEETING ABSTRACT

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