Document 1062
 DOCN  M94A1062
 TI    A comparison of the quality of life of HIV positive patients and healthy
       controls.
 DT    9412
 AU    Jackson LS; Bukar JG; Gesundheit N; Deasy CA; Genentech, Inc., So. San
       Fran., CA.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):218 (abstract no. PB0886). Unique
       Identifier : AIDSLINE ICA10/94371513
 AB    OBJECTIVE: The objective of this analysis was to compare the quality of
       life (QOL) of wasted HIV-1+ (H) patients (pts) and healthy controls (C).
       METHODS: The QOL of 21 H was compared to 18 C utilizing a modified
       version of the MOS-30 QOL form. The modified QOL form contained 18
       questions which were rated on a 5-point scale. Scores were transformed
       linearly from 0 (poor) to 100 (best). The form was completed by H and C
       pts in < 5 minutes. Pts with infections, diarrhea, known malabsorption
       or dysphagia were excluded. Baseline characteristics were: Wt (H:65.3
       +/- 4.2 kg; C: 70.0 +/- 7.1 kg) and BMI (H: 20.6 +/- 1.6; C: 22.1 +/-
       1.6). The QOL form contained 5 major categories: Wt Perception (WP),
       Appearance (App), Physical Functioning (PF), Role Functioning (RF) and
       Energy/Fatigue (EF). RESULTS: TABULAR DATA, SEE ABSTRACT VOLUME. All QOL
       domains were significantly decreased in the H pts, with the exception of
       RF. PF (R = 0.91) and RF (R = 0.87) correlated with overall QOL in H,
       but not in C. CONCLUSION: The H pts perception of their Wt, App, PF, and
       EF was poor and had a negative impact on their overall QOL. New
       therapies directed at increasing wt may have a positive impact on QOL.
 DE    Attitude to Health  Comparative Study  Human  *HIV
       Seropositivity/COMPLICATIONS/PSYCHOLOGY  *Quality of Life  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).