Document 1065 DOCN M94A1065 TI Outcome on the use of a Chinese herbal drug marvel on AIDS patients in Kenya. DT 9412 AU Duan R; Kenya Chinese Medical Center, Nairobi. SO Int Conf AIDS. 1994 Aug 7-12;10(2):217 (abstract no. PB0880). Unique Identifier : AIDSLINE ICA10/94371510 AB OBJECTIVE: To determine the efficacy of a Chinese herbal drug Marvel in the management of AIDS patients. METHODS: 239 confirmed AIDS cases with positive ELISA and WESTERN blot tests and with WHO clinical definition of AIDS--including fever, loss of weight, diarrhoea, chestpains, cough and itching among others; were seen between March 1992 to September 1993. They were given orally a total daily dose of 1.6g (0.8g x 2) for twenty two days and then a break of six days before start of another course. RESULTS: 225 patients were seen and treated in less than 200 days while 14 continued their course for more than 200 days. Of those that took treatment for 6 months and less; diarrhoea, fever, chestpains, cough among others disappeared. Weight gain was the most immediate observation with an average increase of 6kgs. Most of those that showed marked clinical improvement in the first two months absconded and were lost to followup. Of the 14 who continued treatment over 200 days four seroconverted to negative. No side effect or toxicity has been observed so far in all patients treated. CONCLUSIONS: Marvel made from Chinese herbs may have supreme functions in improving body immunity and curing HIV infection. A controlled clinical trial to monitor the immunological and virological parameters e.g. CD4, CD8, B2-microglobulin, neopterin and HIV antibody titre is being set-up to assess the performance of the drug. DE Acquired Immunodeficiency Syndrome/*THERAPY Drugs, Chinese Herbal/*THERAPEUTIC USE Human MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).