Document 1077
 DOCN  M94A1077
 TI    Clinical observation on treating 112 HIV-AIDS patients with Glyke.
 DT    9412
 AU    Lu W; China Academy of TCM, Beijing.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):214 (abstract no. PB0868). Unique
       Identifier : AIDSLINE ICA10/94371498
 AB    OBJECTIVE: To observe the efficacy of GLYKE, a Chinese herbal medicine,
       in treating HIV/AIDS pts. METHODS: 112 HIV/AIDS pts (AC 15, ARC 25, AIDS
       72) were treated with GLYKE, 60mg b.i.d. oral taken for 3-6 months or
       more. Before and after treatment, T4/T8 ratio and T4CC were determined.
       PCR and p24 antigen tests were done also. FACScan and monoclonal
       antibody reagent were used. RESULTS: 3 pta marked effective, 10
       effective, 39 partial effective, total effective rate 46.43%. 33 pts
       with T4/T8 ratio and T4CC improvement were observed. Fatigue, anorexia,
       wasting ameliorated. 3 pts showed seronegative conversion. PCR was done
       in 1 pt, it revealed positive. DISCUSSION AND CONCLUSION: GLYKE is
       effective in treating HIV/AIDS (62.4% were AIDS). 30% of them improved
       immunologically, symptoms ameliorated accordingly. 3 pts showed
       seronegative conversion after GLYKE therapy, but PCR still showed (+).
 DE    Acquired Immunodeficiency Syndrome/IMMUNOLOGY/THERAPY  CD4-CD8 Ratio
       Drugs, Chinese Herbal/*THERAPEUTIC USE  Human  HIV Core Protein
       p24/ANALYSIS  HIV Infections/IMMUNOLOGY/*THERAPY  CLINICAL TRIAL
       MEETING ABSTRACT

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       protected by Copyright Law (Title 17, U.S.Code).