Document 1090
 DOCN  M94A1090
 TI    A trial procedure on HIV infected pregnant women.
 DT    9412
 AU    Miyazawa Y; Ogura Y; Okada K; Inomata Y; Department of OB/GYN, Tokyo
       Metropolitan Otsuka Hospital.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):211 (abstract no. PB0856). Unique
       Identifier : AIDSLINE ICA10/94371485
 AB    OBJECTIVE: Although HIV infected women with pregnancy are not so popular
       yet in Japan, making a guideline of the management for them is growing
       in importance. 8 cases of HIV infected pregnant women were treated in
       our hospital to aim at 1) Delaying the onset of HIV related disease of
       mothers. 2) Protecting neonates from mother-to-child transmission. 3)
       Preventing the transmission to health care workers. 4) Keeping the
       privacy of patients. METHODS: A project team was organized, and then the
       procedures were considered for the delivery or operation as follows; 1)
       Explore and cope with the immuno state and the complication of other
       infectious desease of the patient. 2)List up instruments and disporsable
       products. 3)Carry out simulations. 4)Perform an elective cesarean
       section before onset of labor (4 cases). 5)Bathing the neonates in 38
       degrees C water and 38 degrees C water containing 1% of povidone iodine.
       6)Inhibition of breast feeding. RESULTS: 1)CD4 count and CD4/CD8 ratio
       were low during and after the end of gestation. 2)Investigation of
       peripheral blood of the newborn, placenta and amniotic fluid by PCR and
       P24 antigen revealed that perinatal transmission of HIV did not seem to
       occur in 4 cases, delivered by cesarean section. (4 cases:artificial
       abortion) 3)No transmission to health care workers. 4)The privacy of the
       patients have been kept. CONCLUSIONS: By the strict managements of HIV
       infected pregnant women, the satisfactory outcomes are expectd. The
       elective cesarean section before the onset of the labor may be the most
       effective manner of preventing the transmission mother-to-child.
 DE    Cesarean Section  Disease Transmission,
       Patient-to-Professional/PREVENTION &  CONTROL  Female  Human  HIV
       Infections/*PREVENTION & CONTROL/TRANSMISSION  Infant, Newborn
       Pregnancy  *Pregnancy Complications, Infectious  MEETING ABSTRACT

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