Document 1091
 DOCN  M94A1091
 TI    Reasons for participating in clinical trials in Brazil.
 DT    9412
 AU    Murta F; Schechter M; Zajdenverg R; Artemenko S; Gay V; AIDS Program,
       Federal University of Rio de Janeiro, Brazil.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):210 (abstract no. PB0854). Unique
       Identifier : AIDSLINE ICA10/94371484
 AB    INTRODUCTION: Brazil has been chosen by WHO to participate in future
       vaccine efficacy trials. In addition, an increasing number of clinical
       trials involving HIV-infected patients are being conducted in developing
       countries. Nevertheless, there are almost no data available concerning
       the motivations for participating in clinical trials in Brazil or other
       developing countries. OBJECTIVE: To investigate motivations for
       participating in clinical trials among HIV-infected individuals in Rio
       de Janeiro. METHOD: A closed questionnaire was applied anonymously to 30
       HIV-infected participants of 2 clinical trials. RESULTS: The reasons
       most frequently cited for participating in clinical trials were the
       desire to find a cure for AIDS, the continuing close contact with the
       health care team and the perception that participation might help
       others. One third of the respondents felt that they were being used as
       guinea pigs. Although most (22) were receiving financial help from the
       trial sponsors, a larger number (25) did not consider monetary
       compensation to play a role in their decision to participate. COMMENTS:
       Our study indicates that the hope of finding a cure for AIDS is the main
       reason for joining clinical trials in Rio de Janeiro. On the other hand,
       lack of financial compensation or the negative image of the
       pharmaceutical industry does not appear to hinder patients' willingness
       to participate in clinical trials.
 DE    Attitude  Brazil  *Clinical Trials  Human  HIV Infections/*PSYCHOLOGY
       Motivation  *Patient Participation  Support, Non-U.S. Gov't  MEETING
       ABSTRACT

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