Document 1099
 DOCN  M94A1099
 TI    HIV status and willingness to participate in HIV vaccine trials in
       Rwanda.
 DT    9412
 AU    Lartigue K; Kantarama G; Haynes-Saanstad K; Gasakerume J; Muska S; Allen
       S
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):209 (abstract no. PB0849). Unique
       Identifier : AIDSLINE ICA10/94371476
 AB    OBJECTIVE: To examine the willingness of high risk urban Rwandans to
       participate in future HIV vaccine trials. METHODS: Projet San Francisco
       in Kigali, Rwanda, conducted 13 two-hour focus group discussions (7-10
       participants each) to identify reservations and motivations regarding
       participation in an HIV vaccine trial. Eleven of the 13 groups consisted
       of individuals previously tested for HIV who were aware of their HIV
       status. These included HIV negative single mothers and single men,
       couples with HIV concordant positive results, and couples with HIV
       discordant results. The remaining 2 groups consisted of individuals
       unaware of their HIV status. RESULTS: Reservations and motivations
       common to all groups included adverse effects such as illness or death,
       incentives and reimbursements for participation, and a difficulty or
       disinterest in understanding the large scope of efficacy trials. HIV
       negative participants showed surprisingly little concern about
       developing a falsely positive test. Married participants emphasized a
       need for their partners' consent and cooperation before deciding to
       participate. Uninfected women with HIV positive spouses worried that
       being vaccinated might reduce their husbands' willingness to use
       condoms. DISCUSSION: Recruitment of volunteers for a future vaccine
       trials in Rwanda will depend on how various obstacles and motivating
       factors particular to different HIV status populations are integrated
       with the planning and execution of the trial.
 DE    *AIDS Vaccines  *Clinical Trials  Female  Human  HIV
       Infections/*PREVENTION & CONTROL  Male  Motivation  Risk Factors  Rwanda
       MEETING ABSTRACT

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