Document 1100
 DOCN  M94A1100
 TI    Determinants of levels of compliance in patients enrolled in a PCP
       prophylaxis protocol (community programs for clinical research on AIDS
       (CPCRA)): baseline data.
 DT    9412
 AU    Besch CL; Morse EV; Simon PM; Bincsik A; Cefali P; Connett J; Child C;
       Costanzo L; Cox L; Landry S; et al; Louisiana Community AIDS Research
       Program, New Orleans.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):209 (abstract no. PB0851). Unique
       Identifier : AIDSLINE ICA10/94371475
 AB    OBJECTIVE: To describe baseline data from a study examining the
       relationship of demographics, psychosocial, lifestyle characteristics
       and Health Belief Model (HBM) premises to differential levels of patient
       compliance. This study is being conducted by the NIH-funded CPCRA, a
       clinical trials program, which conducts AIDS research in community
       settings, specifically targeting minorities, women and injectable drug
       users (IDU). METHODS: Data are gathered in a prospective, multicenter
       observational study design by means of patient self-report and clinician
       interview. Data presented are based on a sample of 375 patients
       participating in a multi-site Pneumocystis carinii pneumonia (PCP)
       protocol. RESULTS: At basline the sample is 87% male, 49%
       African-American and 9% Latino/Hispanic. 31% have a history of injection
       drug use, 28% have a history of drinking problems (80% are not currently
       under treatment), 52% have used street drugs other than marijuana (76%
       are not currently under treatment), and 16% have attempted suicide. 61%
       percent report having friends or family who are HIV infected. HBM data
       indicate that only 18% participate in protocol for altruistic reasons
       alone. Second, 70% report no prior study participation. 94% perceive
       that being HIV infected is serious and 64% feel AIDS is the worst
       disease one can have. But, only 34% feel participating in the PCP
       protocol would prevent them from getting sicker. 85% perceived little or
       no trouble to being on the protocol. CONCLUSIONS: Baseline data indicate
       patients perceive low levels of potential medical benefit from protocol
       participation and have high frequencies of untreated substance abuse.
       These data suggest that patient compliance may be difficult to maintain
       at acceptable levels without programatic interventions.
 DE    AIDS-Related Opportunistic Infections/*PREVENTION & CONTROL  Female
       Human  Male  *Patient Compliance  Pneumonia, Pneumocystis
       carinii/*PREVENTION & CONTROL  Prospective Studies  Risk Factors
       MEETING ABSTRACT  MULTICENTER STUDY

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