Document 1103 DOCN M94A1103 TI Immunological aspects of HIV infection. DT 9412 AU Khaitov R; Prokopenko VD; Sidorovitch IG; Trubcheninova LP; Nikolaeva IA; Papuashvily MN; Simonova AV; Institute of Immunology, RF Ministry of Public Health, Moscow,; Russia. SO Int Conf AIDS. 1994 Aug 7-12;10(2):208 (abstract no. PB0845). Unique Identifier : AIDSLINE ICA10/94371472 AB OBJECTIVE. Immunological monitoring of the group of HIV patients. Evaluation of the disease stage and the efficacy of therapeutic approaches. METHODS. Since 1985, the group of HIV-infected patients was under clinical and immunological investigation. RESULTS. The correlation between the parameters of immune status (CD5, CD2, CD4, CD8, CD10, CD3) and viral antigen levels in blood and urine was established. The use of Tat-blocking compounds for treatment of patients with severe AIDS was shown to lead to remission, followed by decrease of HIV antigenemia. DISCUSSION AND CONCLUSIONS. The best clinico-immunological effect and the more favourable prognosis in regards to survival length can be achieved in the case of early intervention using combined therapy. DE Antigens, CD/ANALYSIS Human HIV Antigens/ANALYSIS HIV Infections/DRUG THERAPY/*IMMUNOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).