Document 1154
 DOCN  M94A1154
 TI    Are cardiac abnormalities related to a poorer vital prognosis in AIDS
       patients?
 DT    9412
 AU    d'Ivernois C; Chene G; Dupon M; Lacut JY; CHU Bordeaux, France.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):197 (abstract no. PB0800). Unique
       Identifier : AIDSLINE ICA10/94371421
 AB    OBJECTIVE: To determine the prognosis value of cardiac abnormalities
       (AN) in AIDS patients. METHODS: Thirty four consecutive patients, whose
       AIDS was diagnosed since less than 1 year, hospitalized between November
       1988 and September 1990 in an Infectious Diseases Unit at the Bordeaux
       University Hospital (France), systematically underwent a physical exam,
       an electrocardiogram (ECG) and an echocardiogram (ECH). They were then
       prospectively followed until December 1992. Survival curves were
       performed by the Kaplan-Meier method and compared by the logrank test.
       RESULTS: At baseline, no patient had heart failure, 9 (26%) patients had
       tachycardia (T), 3 (9%) had an ECG AN, 11 (38%) had an ECH AN. By the
       end of the study (639 patients-months), no patient was lost to
       follow-up, 29 (85%) had died, the median survival time was 419 days.
       Although not significant, T seems to be associated with a poorer outcome
       (1-year survival rate: 22% in patients with T, compared to 72% without
       T). The presence of an ECG or an ECH AN was not associated with a
       shorter survival time. DISCUSSION AND CONCLUSIONS: ECG or ECH AN are not
       related to a poorer vital prognosis in AIDS patients with no cardiac
       symptoms at baseline.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/MORTALITY
       Echocardiography  Electrocardiography  Heart
       Diseases/*COMPLICATIONS/DIAGNOSIS  Human  Prognosis  Prospective Studies
       Survival Rate  MEETING ABSTRACT

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