Document 1160
 DOCN  M94A1160
 TI    Malnutrition and survival in AIDS.
 DT    9412
 AU    Dickerson C; Salvato P; Thompson C; Houston Immunological Institute, TX.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(2):195 (abstract no. PB0795). Unique
       Identifier : AIDSLINE ICA10/94371415
 AB    OBJECTIVE: Malnutrition, as measured by serum albumin level and percent
       weight loss, was assessed from the time of initial visit until death.
       METHODS: 112 patients with AIDS (CD4 < 200) were evaluated
       retrospectively by chart review over a 6-year period to determine the
       relationship between malnutrition and survival in AIDS patients.
       RESULTS: AIDS patients with albumin levels > 3.5 gms/dl had a median
       survival of 34 months. AIDS patients with albumin levels < 2.5 gms/dl
       had a median survival of 6 months. Weight loss < 10% of usual body
       weight median survival was 19 months. Weight loss > 20% of usual body
       weight median survival was 7 months. CONCLUSIONS: Malnutrition in AIDS,
       as measured by serum albumin level and percent weight loss, is a
       significant factor in survival. AIDS patients, with normal serum albumin
       levels survived an average of 28 months (5.5 times) longer than those
       patients with low albumin levels < 2.5. Patients with weight loss < 10%
       of usual body weight survived 12 months (2.5 times) longer than patients
       with > 20% weight loss. Length of survival is reasonably predictable
       based on serum albumin level and percent of weight loss.
 DE    Acquired Immunodeficiency Syndrome/*COMPLICATIONS/MORTALITY  Human
       Nutrition Disorders/BLOOD/*COMPLICATIONS  Retrospective Studies  Serum
       Albumin/ANALYSIS  Time Factors  Weight Loss  MEETING ABSTRACT

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