Document 2149
 DOCN  M94A2149
 TI    1993 European AIDS case definition: impact on surveillance.
 DT    9412
 AU    Ancelle-Park R; Alix J; Dubois D; Brunet JB; European Centre for the
       Epidemiological Monitoring of AIDS,; Saint-Maurice, France.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):37 (abstract no. 122C). Unique
       Identifier : AIDSLINE ICA10/94370426
 AB    AIMS: To determine the impact of the expanded 1993 European AIDS case
       definition on the distribution of adult AIDS cases in Europe. METHODS:
       The 1993 European AIDS surveillance case definition, implemented in the
       European region in 1993, comprises three new indicator diseases
       (pulmonary tuberculosis, recurrent pneumonia and invasive cervical
       cancer). Its impact on the surveillance of AIDS (defined as the total
       number of adult AIDS cases fitting solely the new case definition
       divided by the total number of AIDS cases diagnosed since the date of
       implementation in each country) was assessed using data from the
       European Non Aggregate AIDS Data Set (ENAADS) updated December 1993. The
       impact was also calculated by country and transmission category.
       RESULTS: A total of 471 AIDS cases fitting solely the new case
       definition were reported in 1993 by 27 of the 45 countries of the WHO
       European Region (impact: 471/9891 = 4.7%). Impact varied by country from
       1.7% in Italy to 10.7% in Portugal and was high in some countries with
       small numbers of AIDS cases. Detailed break-down of 421 cases was
       available for 14 countries. In these countries 30% of the cases fitting
       solely the new definition were female, 65% presented with pulmonary
       tuberculosis, 28% with recurrent pneumonia and 7.4% with invasive
       cervical cancer. The impact by transmission category was: 7.6% for the
       heterosexual contact group, 5.7% for the injecting drug users (IDU), and
       2.6% for the homo/bisexual group. CONCLUSION: At present the overall
       impact of the expanded 1993 AIDS case definition on surveillance is
       small (4.7%), although it remains to be assessed over a longer time
       period. Nevertheless the impact is more substantial in some countries
       and some transmission categories (heterosexual contact, IDU) and its
       implementation has enabled to better encompass the most severe
       manifestations of HIV infection.
 DE    Acquired Immunodeficiency Syndrome/DIAGNOSIS/*EPIDEMIOLOGY/
       TRANSMISSION  Adult  AIDS-Related Opportunistic Infections/*DIAGNOSIS
       Cervix Neoplasms/*DIAGNOSIS  Europe/EPIDEMIOLOGY  Female  Human  Male
       Pneumonia/DIAGNOSIS  Population Surveillance  Risk Factors
       Tuberculosis, Pulmonary/DIAGNOSIS  MEETING ABSTRACT

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