Document 2150
 DOCN  M94A2150
 TI    The impact of the 1993 expanded AIDS surveillance definition on
       diagnosis and reporting of AIDS in the USA.
 DT    9412
 AU    Ward JW; Green T; Division of HIV/AIDS, CDC, Atlanta, GA.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):37 (abstract no. 121C). Unique
       Identifier : AIDSLINE ICA10/94370425
 AB    OBJECTIVE: To examine the effect of adding new criteria (NEW) [severe
       immunosuppression (SI) < 200 CD4+ cells/microL, CD4+ < 14%, pulmonary
       TB, recurrent pneumonia, and invasive cervical cancer] on January 1,
       1993 to the pre-1993 (OLD) AIDS reporting criteria. METHODS: We compared
       NEW AIDS cases with OLD cases reported in 1993 and 1992. For diagnosis
       dates (DX), data were adjusted for reporting delay; for SI cases, OLD
       AIDS DX were estimated using data from a clinic-based study of 23,000
       HIV-infected persons. RESULTS: Of the 103,500 AIDS cases reported in
       1993; 55,432 (54%) were NEW cases and 48,068 were OLD cases; 91% of NEW
       cases were SI cases. From 1992 to 1993, reporting increased 111%
       overall, 152% in women vs. 105% in men, 123% in blacks vs. 102% in
       whites, 214% in 13-19 y.o. vs. 112% in 30-39 y.o., and 136% in injecting
       drug users (IDU) vs. 87% in homo/bisexual men. Persons with NEW AIDS
       were more likely than those with OLD to be women (17% vs. 15%), black
       (37% vs. 35%), IDU (29% vs. 26%), and living (88% vs. 66%), and to have
       higher CD4+ values (121 cells/microL vs. 44). Of the 5,371 persons with
       NEW opportunistic illnesses, 26% were women, 63% black, and 48% were
       IDU. Trends in diagnosis were as follows. TABULAR DATA, SEE ABSTRACT
       VOLUME DISCUSSION: The expanded definition has increased AIDS reporting,
       includes persons in earlier stages of HIV disease, and better
       characterizes persons with HIV-related SI and disease. Estimates of AIDS
       DX trends must take into account the addition of SI reporting.
 DE    Acquired Immunodeficiency Syndrome/DIAGNOSIS/*EPIDEMIOLOGY  Adolescence
       Adult  AIDS-Related Opportunistic Infections/*DIAGNOSIS  Cervix
       Neoplasms/DIAGNOSIS  Female  Human  Leukocyte Count  Male
       Pneumonia/DIAGNOSIS  Risk Factors  Tuberculosis, Pulmonary/DIAGNOSIS  T4
       Lymphocytes  United States/EPIDEMIOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).