Document 2152 DOCN M94A2152 TI HIV seroprevalence trends in the United States 1988-1992. DT 9412 AU Petersen LR; Gwinn M; Janssen R; Centers for Disease Control and Prevention, Atlanta, GA. SO Int Conf AIDS. 1994 Aug 7-12;10(1):37 (abstract no. 123C). Unique Identifier : AIDSLINE ICA10/94370423 AB OBJECTIVE: Determine trends in HIV-1 seroprevalence among sentinel populations in the United States. METHODS: We reviewed seroprevalence data from annual anonymous [unlinked] surveys among childbearing women (N = 9,000,000) and clients of sexually transmitted disease (STD) clinics (N = 349,000) and drug treatment (DT) clinics (N = 43,500) in 40 cities and from national routine screening of military applicants (N = 3,726,000), disadvantaged youth entering a national job training program (Job Corps; N = 270,000), and first-time blood donors (N = 7,205,000). We compared rates for 1989-90 surveys with rates in 1991-92. RESULTS: During 1991-92, prevalence exceeded 15% among men who had sex with men (MSM) in nearly every STD clinic (median 26%); the absolute HIV prevalence decreased by a median of 5.7% from 1989-90. In contrast, prevalence in 1991-92 among injection drug users (IDU) entering DT ranged from 15-40% in eastern cities and was < 7% elsewhere, without a clear trend in prevalence. Prevalence among men applying for military service, entering the Job Corps, and donating blood decreased markedly, while prevalence among women remained stable or increased. In these populations, seroprevalence in women now is nearly equal to or exceeds that of men. Prevalence among childbearing women increased from 0.16% in 1989-90 to 0.17% in 1991-92, with decreasing trends in the Northeast and increasing trends in the South, particularly among blacks. CONCLUSION: Prevalence among men is generally decreasing, particularly among MSM attending STD clinics, while prevalence among women is stable or increasing. Prevalence among IDUs entering DT did not change. These results indicate a substantial shift in the HIV epidemic, with greater relative importance of HIV in women, IDUs and African Americans. DE Female Homosexuality Human HIV Seroprevalence/*TRENDS Male *Population Surveillance Pregnancy Pregnancy Complications, Infectious Risk Factors Seroepidemiologic Methods Sexually Transmitted Diseases/COMPLICATIONS Substance Abuse, Intravenous/COMPLICATIONS United States/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).