Document 2249 DOCN M94A2249 TI HIV-1 seroprevalence among gay and bisexual (gay/bi) men attending sexually transmitted disease (STD) clinics in California. DT 9412 AU Ruiz JD; Wilson D; Mikanda J; Littaua R; Kerndt P; Lemp G; California Dept of Health Services, Sacramento 95814. SO Int Conf AIDS. 1994 Aug 7-12;10(1):347 (abstract no. PC0620). Unique Identifier : AIDSLINE ICA10/94370326 AB OBJECTIVE: To assess regional HIV-1 seroprevalence and associated risk factors among gay/bi men attending STD clinics in California. METHODS: Using standardized protocols developed by the Centers for Disease Control and Prevention, we tested unlinked serum specimens from 9,776 gay/bi men attending 23 STD clinics of California's 61 local health jurisdictions between 1989 and 1992. We analyzed risk factors for HIV-1 using logistic regression and trends in HIV-1 seroprevalence using X2 test for linear trend. RESULTS: TABULAR DATA, SEE ABSTRACT VOLUME. Using white gay/bi men as the reference group, the odds for HIV-1 infection was highest among African American men (OR = 1.7 95% CI 1.5-2.0). Using California Valley as the reference group, the odds for HIV-1 infection was highest in San Diego (OR = 2.7 95% CI 2.1-3.4), San Francisco (OR = 2.6 95% CI 2.2-3.2), Los Angeles (OR = 2.0 95% CI 1.7-2.4), and Central Coast (OR = 1.7 95% CI 1.3-2.2). Factors associated with HIV-1 infection included age over 25 years (OR = 2.2 95% CI 2.0-2.5), and history of injection drug use since 1978 (OR = 1.5 95% CI 1.3-1.7). CONCLUSION: HIV-1 seroprevalence declined for gay/bi men in STD clinics in California. Regionally, gay/bi men attending STD clinics in San Diego, San Francisco, and Los Angeles were more likely to be HIV-1 infected. Regional information is valuable for prevention efforts in local communities. DE Adult Bisexuality/*STATISTICS & NUMER DATA California/EPIDEMIOLOGY Homosexuality/*STATISTICS & NUMER DATA Human HIV Infections/*EPIDEMIOLOGY/PREVENTION & CONTROL/TRANSMISSION *HIV Seroprevalence *HIV-1 Male Negroid Race Risk Factors Sexually Transmitted Diseases/*EPIDEMIOLOGY/PREVENTION & CONTROL/ TRANSMISSION MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).