Document 2250
 DOCN  M94A2250
 TI    HIV and HCV prevalence in childbearing women at outcome of pregnancy in
       the Paris area, France.
 DT    9412
 AU    Couturier E; Six C; Brossard Y; Larsen M; Henrion R; Brunet JB; European
       Centre for the Epidemiological Monitoring of AIDS,; Saint-Maurice,
       France.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):347 (abstract no. PC0618). Unique
       Identifier : AIDSLINE ICA10/94370325
 AB    OBJECTIVE: To determine the prevalence of HIV and HCV infection in
       childbearing women at outcome of pregnancy (deliveries, abortions,
       ectopic pregnancies) in all medical settings in the Paris area. METHODS:
       Blood samples were collected on filter papers for all women in all
       medical settings (public and private) during a 4-week period in 1993.
       For each woman, variables included pregnancy outcome, age, residence
       area code and country of birth. Unlinked HIV antibody testing was
       carried out on all filter papers. Unlinked HCV testing (ORTHO HCV 3.0
       and CHIRON RIBA 3.0) was carried out on a stratified sample: 1 out of 2
       for women born in France and all papers in foreign born women. RESULTS:
       Out of 10,617 papers collected, 7,072 had both tests performed. HIV
       prevalence was 0.6% [95% CI 0.4-0.7] and weighted HCV prevalence
       estimate was 1.3% [95% CI 1.0-1.6]. HCV and HIV prevalences by pregnancy
       outcome are shown in the table for women with a known outcome. TABULAR
       DATA, SEE ABSTRACT VOLUME. HCV estimates were not different by
       country/region of birth (France: 1.4%; N. Africa: 1.5%; Subsaharan
       Africa/the Caribbean: 1.6%; other countries: 0.8%). In contrast, HIV
       prevalences differ by country/region (respectively, 0.4%, 0.4%, 1.7%,
       0%). HIV prevalence was 13% for HCV (+) women compared to 0.4% for HCV
       (-) women. CONCLUSION: This unlinked exhaustive survey of childbearing
       women allows estimates of HCV and HIV prevalence. HCV estimates are high
       in this heterosexual population. For women undergoing abortion, results
       are consistent with a possible common risk factor (IV drug use) for HCV
       and HIV transmission.
 DE    Abortion, Legal  Adult  Female  Hepatitis C/*EPIDEMIOLOGY/TRANSMISSION
       Human  HIV Infections/*EPIDEMIOLOGY/TRANSMISSION  HIV Seroprevalence
       Infant, Newborn  Paris/EPIDEMIOLOGY  Pregnancy  Pregnancy Complications,
       Infectious/*EPIDEMIOLOGY/ETIOLOGY  Pregnancy Outcome  Risk Factors
       Urban Population/*STATISTICS & NUMER DATA  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).