Document 2282
 DOCN  M94A2282
 TI    Incidence of HIV infection among women in Dar-Es-Salaam, Tanzania.
 DT    9412
 AU    Shao JF; Kapiga SH; Lwihula G; Hunter DJ; University of Dar-es-Salaam,
       Tanzania.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):34 (abstract no. 108C). Unique
       Identifier : AIDSLINE ICA10/94370293
 AB    OBJECTIVES: To determine incidence of HIV-1 infection and associated
       factors among women at three family planning clinics in Dar-es-Salaam.
       METHODS: Beginning in October 1992 women who were HIV-ve in the
       cross-sectional survey (conducted between Feb 1991 and June 1992) were
       invited to participate in a prospective study. After informed consent
       subjects were interviewed and genital swabs & blood collected for
       laboratory diagnosis of STD's and HIV-1 infection. So far we have
       enrolled 754 women and the average duration of follow-up is 14 months.
       RESULTS: Out of 754 subjects, 27 were found to be HIV positive
       (cumulative incidence = 3.6%). Compared to older women, women < 20 years
       were 3 times more likely to seroconvert (RR = 2.8; 95% CI = 1.0-7.8).
       HIV seroconversion was high among unmarried cohabiting women (5.9%) than
       among married women (2.9%). Number of sex partners in the last 5 years
       was associated with new HIV infections: 1 partner, (3.5%); 2,3 (2.9%);
       4+ partners (8.2%). Seroconversion was more likely to occur among women
       reporting to have sex with men other than their spouse (4.9%) than among
       women not reporting such history (3.4%). Risk of seroconversion was
       moderately increased among women with laboratory confirmed STD's (RR =
       1.3; 95% CI = 0.71-2.36). HIV incidence did not vary with contraceptive
       use. CONCLUSION: These results indicate continued spread of HIV
       infection in this population. Strategies aiming at changing high risk
       behavior and STD control are needed to prevent further spread of HIV
       infection.
 DE    Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY  Adolescence  Adult
       Age Factors  Cross-Sectional Studies  Female  Human  HIV
       Infections/DIAGNOSIS  HIV Seropositivity  *HIV-1  Incidence  Prospective
       Studies  Sex Behavior  Sexual Partners  Sexually Transmitted
       Diseases/DIAGNOSIS  Tanzania/EPIDEMIOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
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