Document 2326
 DOCN  M94A2326
 TI    Gender specific HIV transmission/prevention in discordant couples in
       rural Uganda.
 DT    9412
 AU    Serwadda D; Gray RH; Sewankambo NK; Wawer MJ; Makerere U; Uganda Virus
       Research Institute, Entebbe.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):33 (abstract no. 107C). Unique
       Identifier : AIDSLINE ICA10/94370249
 AB    OBJECTIVE: To determine the role of males and females as sources of HIV
       infection among discordant couples in rural Rakai, Uganda. METHODS:
       Annual serological and behavioral surveys were conducted in a population
       based cohort. Thirty one community clusters were randomly selected from
       three strata: trading centers (TCs) on main roads, trading villages
       (TVs) on secondary roads, and agricultural villages (AVs) off-roads. In
       1990, serological data were available for both members of 83 discordant
       couples aged 13-49 years. RESULTS: The female was the seropositive
       member in 35 (42%) of the 83 couples. There was marked variation in the
       gender of the seropositive partner by place of residence. The female was
       the positive partner in 17/30 (57%) of TC couples, 12/23 (52%) of TV
       couples, and in only 6/30 (20%) of AV couples (P < 0.05). These
       differences suggest that in TCs women are at high risk of introducing
       infection in the couple, whereas men are the predominant source of new
       infections in rural village couples. A noteworthy finding was that if
       the husband was negative and the wife seropositive, condom use was
       17.1%; whereas if the male was HIV positive and the female negative
       condom use was only 6.8%. CONCLUSION: The gender-specific source of
       infection into a family varies between communities. In the agricultural
       villages, males appear to be the predominant source of new infections.
       In addition preventive behaviors, may be associated with the gender of
       the infected partner.
 DE    Adolescence  Adult  Cohort Studies  Condoms/UTILIZATION  Female  Human
       HIV Infections/PREVENTION & CONTROL/*TRANSMISSION  HIV
       Seropositivity/EPIDEMIOLOGY  Male  Middle Age  Population Surveillance
       Rural Population  Sampling Studies  Sex Factors  Sexual Partners
       Uganda/EPIDEMIOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).