Document 2331
 DOCN  M94A2331
 TI    Changes in the laboratory test require during the spread of HIV
       infection in Rosario, Argentina.
 DT    9412
 AU    Taborda M; Rubio L; Rodenas E; Ghioni G; Fernandez E; Fay O; Center for
       Technology in Public Health, National University of; Rosario, Argentina.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):329 (abstract no. PC0249). Unique
       Identifier : AIDSLINE ICA10/94370244
 AB    OBJECTIVE: To implement a Reference Center for HIV surveillance and
       support the medical requirement of laboratory test for the follow up of
       HIV infected people. INTRODUCTION: Since 1986 our Center incorporated
       the HIV screening among volunteer blood donors in Public Health services
       located in Rosario City. The transfer of technology and training were
       promoted in the Northeast part of Argentina, comprising 20% of the
       entire country population. After seven years a network was set up with
       the integration of 42 blood banks and 31 Medical Centers inside the
       region. 74 people received training. We evaluate in the last two years
       the serological test other than Elisa and Western blot for HIV, for
       medical assistance of HIV infected people. RESULTS: 10904 spontaneous
       and anonymous presentation for HIV screening, and 241114 volunteer blood
       donors were tested for HIV positivity during the follow up. 3362 were
       confirmed as HIV positive and belong to different at risk communities
       from the area incorporated to the network. 813 test for HIVAg, 8215 for
       HVB, 3810 for TBC and 2117 CD4/CD8 count were performed. Organon Teknika
       and Abbott laboratory Elisa test were used for HIV and HVB tests.
       Western blot and LiaTek from Organon were used for confirmatory test,
       CD4/CD8 count by IFA was used. Figure I and II show the evolution of
       different number of test during the time considered. DISCUSSION: The
       establishment of a Reference Center for HIV surveillance and the
       permanent implementation of new technologies in laboratory work to
       assist the requirement of HIV infected people, demand a precise aim
       definition. Different test other than HIV related are necessary for
       medical evaluation, therapy monitoring, house holders evaluation, etc.
       Permanent training and transfer of technology to set up a network in
       order to assist the HIV spread is necessary. Our experience allow us to
       submit the following. CONCLUSIONS: 1) In developing countries the HIV
       infection generate a permanent implementation of different laboratory
       test in order to answer the medical and social requirement of the
       infected people. 2) The purposes of Reference Center must be analysed
       steadily in order to establish a enough budget for its continuity.
       TABULAR DATA, SEE ABSTRACT VOLUME.
 DE    Argentina/EPIDEMIOLOGY  AIDS Serodiagnosis/*STATISTICS & NUMER DATA
       Blood Donors/*STATISTICS & NUMER DATA  Blotting, Western  CD4-CD8 Ratio
       *Developing Countries  Enzyme-Linked Immunosorbent Assay  Follow-Up
       Studies  Human  HIV Infections/*EPIDEMIOLOGY/PREVENTION &
       CONTROL/TRANSMISSION  *Mass Screening  *Population Surveillance
       Predictive Value of Tests  MEETING ABSTRACT

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