Document 2339
 DOCN  M94A2339
 TI    A simplified paediatric AIDS case definition for use where HIV testing
       is available.
 DT    9412
 AU    Loures L; Gianna M; Negra M; Succi R; Barreira D; Rubini N; Lauria L;
       National STD/AIDS Programme, Ministry of Health, Brasilia, DF,; Brazil.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):327 (abstract no. PC0241). Unique
       Identifier : AIDSLINE ICA10/94370236
 AB    The surveillance AIDS case definition in children, which was adopted by
       the Ministry of Health (MOH)-Brazil in 1987, had low sensitivity and
       utilized unrealistic criteria for diagnosis of opportunistic diseases.
       WHO pediatric AIDS case definition has been found with low sensitivity
       (21%), when tested in Brazil. In response to the need for a surveillance
       definition more sensitive that not require special and expensive
       laboratory tests, a simplified case definition was drafted through a
       consensus of experts coordinated by the MOH. For epidemiological
       surveillance a child (< 13 years) is considered to have AIDS if he has a
       positive laboratory result for HIV, and at least two of the following
       major signs or one major sign associated with at least two of the
       following minor signs: Major signs: Oral candidiasis resistent to
       regular therapy, Parotid chronic hyperplasia, Chronic or recurrent
       diarrhea, Herpes zoster, Tuberculosis. Minor signs: Chronic or recurrent
       otitis or sinusitis, Hepatomegaly or splenomegaly, Myocardiopathy,
       Chronic dermatitis, Lymphadenopathy (> = 0.5 cm and > 2 sites),
       Prolonged fever (> = 38 C and > = 1 month or recurrent), Weight loss (>
       10% of baseline body weight) or abnormally growth curve, Anemia and or
       lymphopenia and or thrombocytopenia. This definition presents the
       following advantages: (1) simple to use; (2) includes tuberculosis and
       (3) high specificity (by the incorporation of HIV serological testing).
       It should be fully evaluated.
 DE    Adolescence  AIDS Serodiagnosis/*STATISTICS & NUMER DATA  AIDS-Related
       Opportunistic Infections/CLASSIFICATION/DIAGNOSIS/  *EPIDEMIOLOGY
       Brazil/EPIDEMIOLOGY  Child  Child, Preschool  Female  Human  HIV
       Infections/CLASSIFICATION/DIAGNOSIS/*EPIDEMIOLOGY  HIV
       Seroprevalence/*TRENDS  Infant  Male  *Population Surveillance  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).