Document 2340
 DOCN  M94A2340
 TI    Results of three consecutive inquiries for HIV infection sentinel
       surveillance among sexually transmitted diseases patients in Porto
       Alegre, RS Brazil.
 DT    9412
 AU    Loureiro R; Balsan M; Ramos M; Silveira V; Becker F; Ferreira J
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):326 (abstract no. PC0237). Unique
       Identifier : AIDSLINE ICA10/94370235
 AB    OBJECTIVE: Estimate Instantaneous Prevalence of HIV infection over time
       in STD patients sentinel population. METHODS: Three inlinked anonymous
       cross-sectional tests with a six-month interval between then;
       consecutive sampling of the first consultation male patients who seek
       care in a free urban STD Clinic; blood collected for VDRL was separeted
       and identified only with date and age group (no other identifier to
       preserve anonymity). Women were excluded (reduced number of female
       patients in the study periods). The sample were achieved in about six
       weeks. Screening test: second generation ELISA. Confirmatory test:
       Indirect Immunofluorescence. Internal/external quality control was
       adopted (State Reference Laboratory). RESULTS: First inquiry
       (may-jun,1992): 18 positive in 400 blood samples, prevalence = 4.5%, SD
       = 1.04; CI = 2.46-6.54 (95%-alpha = 0.05); 2.80-6.20 (90%-alpha = 0.10).
       Second inquiry (nov-dec,1992): 20 in 400 blood samples were positive
       with a prevalence of 5.0%; SD = 1.08; CI = 2.88-7.12 (95%-alpha = 0.05);
       3.23-6.77 (90%-alpha = 0.10). Third inquiry (may-jun,1993): 22 positive
       in 408 blood samples, prevalence: 5.4%; SD = 1.12; CI = 3.21-7.59
       (95%-alpha = 0.05); 3.56-7.24 (90%-alpha = 0.10). CONCLUSIONS: The
       founds reveals high prevalences among high-risk population, but no
       significant difference were observed between the first and the two
       subsequent studies. Probabily a six-month interval is very small to
       identify prevalence changes in this population. So the decision was to
       follow the studies with a twelve-month intervals between eat inquiry. We
       demonstrated the feasibility and usefulness of the sentinel surveillance
       of HIV infection proposed by GPA/WHO to orient prevention and control
       activities. The anonymous inlinked method avoid participation bias.
 DE    Adult  Brazil/EPIDEMIOLOGY  Cross-Sectional Studies  *Developing
       Countries  Enzyme-Linked Immunosorbent Assay  Human  HIV
       Infections/*EPIDEMIOLOGY/TRANSMISSION  Incidence  Male  *Population
       Surveillance  Sexually Transmitted Diseases/*EPIDEMIOLOGY/TRANSMISSION
       MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).