Document 2352 DOCN M94A2352 TI Silicone application as a risk factor for HIV infection. DT 9412 AU Goihman S; Ferreira A; Santos S; Grandi JL; Reference and Training Center/AIDS-Paulista School of Medicine,; Sao Paulo, Brazil. SO Int Conf AIDS. 1994 Aug 7-12;10(1):323 (abstract no. PC0223). Unique Identifier : AIDSLINE ICA10/94370223 AB OBJECTIVE: To study usual practices of feminization amon transvestites and to establish the relationship between the application of silicone and the HIV infection. METHODS: A random sub-sample size 75 was drawn from a sample transvestites included by peer recruitment on an AIDS Prevention Study Cohort. A standard quastionnaire was applied from october to december 1993. Results from HIV tests were availabe from 70 subjects. RESULTS: 52 (71.4%) transvestites used silicone (50 of them with HIV tests). Only 3 (5.8%) of them has injected silicone by doctors. The application for 49 (94.2%) was done by others transvestites which used industrial silicone and a non-disposable syringe and needle. The same kit was used many times without appropriate care. 29 (58.0%) of the silicone users and 5 (25.0%) between the non-users were HIV positive (X2 = 6.227; p < 0.02). DISCUSSION AND CONCLUSIONS: The application of silicone may be an additional factor of HIV transmission. A multivariate analysis is being conducted to establish potential confounders. DE Cohort Studies Human HIV Infections/PREVENTION & CONTROL/*TRANSMISSION Injections, Subcutaneous Male Needle Sharing/*ADVERSE EFFECTS Risk Factors Silicones/*ADMINISTRATION & DOSAGE Transvestism/*COMPLICATIONS MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).