Document 2353
 DOCN  M94A2353
 TI    Seroconversion time and its possible relation with the way of infection.
 DT    9412
 AU    Fay O; Fernandez E; Rodenas E; Taborda M; Galante N; Viglianco R; Center
       for Technology in Public Health, National University of; Rosario,
       Argentina.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):323 (abstract no. PC0222). Unique
       Identifier : AIDSLINE ICA10/94370222
 AB    OBJECTIVE: To compared the time of seroconversion from indeterminate to
       positive Western blot among HIV infected patients by blood or
       heterosexual way. METHODS: During six years 3,362 HIV positive carriers
       were found among 266,175 spontaneous presentation to our Centre from
       different risk groups. We were able to establish a follow up among 24
       people who acquire HIV infection and remain out of risk. 13 (54%) were
       infected by heterosexual way and 11 (46%) were IVDU. Organon Teknika and
       Abbott Laboratory Elisa test were runned for screening and Western blot
       and LiaTek from Organon were used for confirmatory assay. Three
       confirmatory tests in each patients was tested. RESULTS: The mean of
       seroconversion time among sex infected people was 11.12 months, whereas
       it was 4.19 months in IVDU and the std.dev is 4.43 and 2.97
       respectively, the t Test for grouped data shows statistical significance
       at p < 0.01. When the sex difference was study, no statistical
       significance was found. Figure I and II shows the results. DISCUSSION
       AND CONCLUSIONS: A small number of infected people had been incorporated
       to the follow up due to the fact that is very difficult to confirm the
       conditions out of risk after HIV infection. Additionally only people
       with confirmation of the way of infection had been included. The results
       allow us these conclusions: 1) The time of seroconversion is different
       when blood to heterosexual HIV transmission is compared. 2) Apparently
       no sex different can be establish for the moment. 3) More information
       related to the virus characteristics must be study to know its
       participation in these seroconversion time. TABULAR DATA, SEE ABSTRACT
       VOLUME.
 DE    *AIDS Serodiagnosis  Blood Transfusion  Blotting, Western  Enzyme-Linked
       Immunosorbent Assay  Female  Follow-Up Studies  Human  HIV
       Antibodies/*ANALYSIS  HIV Seropositivity/IMMUNOLOGY/*TRANSMISSION  Male
       Sex Behavior  Substance Abuse, Intravenous/COMPLICATIONS/IMMUNOLOGY
       Time Factors  MEETING ABSTRACT

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