Document 2366 DOCN M94A2366 TI Natural history of AIDS in the city of Sao Paulo. DT 9412 AU Figueiredo GM; Lagonegro E; Buchala CM SO Int Conf AIDS. 1994 Aug 7-12;10(1):320 (abstract no. PC0212). Unique Identifier : AIDSLINE ICA10/94370209 AB AIDS has been an important public health problem in Brazil. The country nowadays ranks a 4th among the whole world. The most recent figures show 45,049 AIDS cases in Brazil from 1980 to 1993, being that 26,143 out of those come from the State of Sao Paulo and 15,455 (34.3%) come only from the City of Sao Paulo. The Surveillance System is active and collects information from hospital patients and from death certificates. This system uses the CDC AIDS case definition. The reported information on AIDS cases are related to the following variables: risk behavior group, age, sex, time of the first symptoms, presence of cancer and/or opportunistic infections. However, this system does not consider the description of the disease process. Therefore, a study on AIDS natural history in the City of Sao Paulo is needed in order to help the earlier diagnosis, to improve the clinical attitudes and also to obtain basic information for the prevention programs for specific groups. METHODS--Clinical data from a cohort of patients registered in the AIDS Reference and Training Centre of the Secretariat of Health of the State of Sao Paulo from 1982 to 1992 will be reviewed. Information on sex, age, risk behavior and clinical evolution including the presence of cancer and opportunistic disease will be collected. The data will be analysed using the COX REGRESSION and KAPLAN MEYER methods so that the AIDS natural history can be described. DE Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY Brazil/EPIDEMIOLOGY Human MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).