Document 2368 DOCN M94A2368 TI Husband HIV discordance among HIV-infected pregnant women, Bangkok, Thailand. DT 9412 AU Roongpisuthipong A; Siriwasin W; Chaiyakul P; Bhiraleus P; Laosakkitiboran J; Shaffer N; Mastro TD; Siriraj Hospital, Mahidol University, Bangkok. SO Int Conf AIDS. 1994 Aug 7-12;10(1):32 (abstract no. 103C). Unique Identifier : AIDSLINE ICA10/94370207 AB OBJECTIVES: To determine the prevalence of HIV-negativity (discordance) among husbands of HIV-positive pregnant women and to compare risk behaviors among wives and husbands in this group. METHODS: At 2 large hospitals in Bangkok with regular antenatal HIV counseling and testing, husbands of HIV-infected pregnant women are also asked to present for HIV counseling and testing. Initially, data on the husbands' risk behavior and HIV status were collected from the women as part of a perinatal transmission study. Since Nov 1993, a new study administers similar questionnaires to both wife and husband to better assess risk behavior and knowledge of partners. RESULTS: Among the first 165 HIV-positive women enrolled during antenatal care in the perinatal transmission study, HIV test results were available for 137 (83%) husbands. Overall, 35/137 (26%) of husbands were HIV-negative (discordant). Husband discordance rates were higher among women who reported > 1 lifetime sex partner (27/67; 40%), compared to women who reported only 1 lifetime sex partner (8/70; 11%) (OR 5.2; p = 0.0001). Of the first 78 partners enrolled in the husband study, 17 (22%) are HIV-negative (discordant). Risk factor analyses are ongoing. CONCLUSIONS: Pregnant women have been extensively surveyed during the HIV epidemic, but little is known about their husbands/partners. While most pregnant women in Bangkok appear to have no identified risk except sex with their husbands, partner testing has revealed that 20-30% of husbands are discordantly negative. This suggests that a subgroup of HIV-infected pregnant women have discordantly negative. This suggests that a subgroup of HIV-infected pregnant women have other risk factors and that heterosexual transmission risk in regular relationships is bidirectional (male-to-female and female-to-male). A better understanding of risk behaviors and perceptions within relationships is needed for appropriate counseling and prevention programs. DE Adult Female Human *HIV Seronegativity HIV Seropositivity/EPIDEMIOLOGY/*PSYCHOLOGY Male Pregnancy *Pregnancy Complications, Infectious Prenatal Care Risk Factors *Risk-Taking Sex Behavior Thailand/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).