Document 2390
 DOCN  M94A2390
 TI    Prevalence of HIV among pregnant women identified at prenatal clinics in
       Brazil.
 DT    9412
 AU    Oliveira R; Perini N; Pinheiro M; Rodrigues L; Sato P; Antunes C; Loures
       L; Department of Health, Brasilia, Brazil.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):315 (abstract no. PC0189). Unique
       Identifier : AIDSLINE ICA10/94370185
 AB    OBJECTIVES: Indicators (Priority Prevention Indicators, PPIs) for
       monitoring National AIDS Programs were developed by GPA/WHO. PPI-5 (HIV
       seroprevalence in pregnant women, 15-24 years, attending prenatal
       clinics, non-linked) was field tested by the Brasilia Public Health
       System (BPHS), in collaboration with the National STD/AIDS Control
       Program, Brazil. METHODS: After identifying all BPHS prenatal clinics
       (49), the participating Centers were selected by systematic sampling,
       based on the number of pregnant women seen at each Center. From each
       enrolled Clinic, 75 samples were to be collected (a total of 1500). All
       pregnant women in their first clinic visit had their age and parity
       recorded. A blood sample was collected in two types of filter paper
       (Whatman 4 and Mellita coffee filter); a serum sample was also obtained
       to be used as a gold-standard. All Whatman filter paper samples, plus a
       random sample of 10% of repeats were tested for HIV using a viral lysate
       ELISA (Abbott). All those testing positive plus a 10% random sample of
       negatives were re-tested by (1) viral lysate Elisa (Mellita coffee
       filter) and (2) recombinant Elisa (serum) plus a confirmatory WB in
       those testing positive (serum). RESULTS: A total of 2729 samples were
       collected; of those, 1789 (65.6%) were in the required age range.
       Preliminary tests (viral lysate Elisa, Whatman 4 samples) were carried
       out in 1044 participants; 2 tested positive. The same results were
       obtained retesting the positive participants plus a 10% repeat of
       negatives, using the Mellita coffee filter (viral lysate Elisa) and
       serum samples (recombinant Elisa). The positive results were confirmed
       by WB. CONCLUSIONS: The inclusion of PPI-5 in the routine of prenatal
       clinics in the BPHS have shown the feasibility of carrying out these
       indicators to monitor NAPs. The results obtained should reflect the risk
       of HIV infection in the age group, since the prenatal program was
       estimated to have a coverage over 90% in the BPHS.
 DE    Adolescence  Adult  Ambulatory Care Facilities  Brazil/EPIDEMIOLOGY
       Enzyme-Linked Immunosorbent Assay  Female  Human  HIV
       Infections/DIAGNOSIS/*EPIDEMIOLOGY  Pregnancy  Pregnancy Complications,
       Infectious/DIAGNOSIS/*EPIDEMIOLOGY  Prenatal Care  Prevalence  MEETING
       ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).