Document 2482
 DOCN  M94A2482
 TI    Heterosexual transmission of HIV. The follow up of 174 couples in the
       period 1985-1993.
 DT    9412
 AU    Falciano M; Bergami N; Rubino L; Macedonio A; Salotti A; Vullo V;
       Turbessi G; Institute of Infectious Diseases, Rome University La
       Sapienza.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):294 (abstract no. PC0105). Unique
       Identifier : AIDSLINE ICA10/94370093
 AB    Recent epidemiological data indicate a clear-cut increase in subjects
       infected heterosexually. The aim of this study is to evaluate the
       factors implicated in heterosexual transmission. During the period
       1985-1993 at the Institute of Infectious Diseases of the University of
       Rome La Sapienza, 174 stable heterosexual couples were observed. Condom
       use and the frequency of intercourse before and after finding out about
       the seropositivity of the partner were examined. The index cases
       subdivided for sex and risk behaviour were thus divided: 140 males (123
       DA, 15 heterosexuals, 2 bisexuals) 34 females (18 DA, 15 heterosexuals,
       1 transfusion). The transmission occurred in 61 couples, 5 from woman to
       man and 56 from man to woman. In 9 cases, seroconversion occurred during
       follow-up. As for the frequency of intercourse before finding out, in
       couples where transmission had not occurred, 32 couples had intercourse
       less than twice a week, 42 couples between 2 and 7 times a week and 16
       couples more than 7 times a week. After finding out about their
       seropositivity, 48 couples had intercourse less than twice a week, 39
       between 2 and 7 times a week, and 10 more than 7 times a week. In
       couples where transmission had occurred, before finding out, 9 couples
       had intercourse less than twice a week, 35 between 2 and 7 times a week,
       and 9 more than 7 times a week. After finding out, 24 couples had
       intercourse less than twice a week, 25 couples between 2 and 7 times a
       week and only 3 more than 7 times a week. As for the use of the condom
       in couples before finding out about the seropositivity of the partner
       with no transmission, 69 couples never used it, 16 sometimes, 5 always.
       After finding out about their seropositivity, only 8 couples never used
       the condom, 17 sometimes, 72 always. Instead with couples where
       transmission had occurred, 47 couples before finding out about their
       seropositivity never used it, 6 sometimes and none always. After finding
       out, 20 couples never used it, 4 sometimes and 28 always. The data show
       that an increased frequency of intercourse as well as non-protection
       favours the transmission of the infection. Thus it is indicated that
       sexual behaviour be modified after finding out the seropositivity of the
       index case.
 DE    Coitus  Female  Human  HIV Infections/*TRANSMISSION  HIV Seropositivity
       Male  *Sex Behavior  MEETING ABSTRACT

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