Document 2520 DOCN M94A2520 TI Seroprevalence of HIV in the Tokyo district. DT 9412 AU Mori K; Sadamasu K; Tabei Y; Inaba M; Yamazaki K; Itoh T; Sekine S; Tokyo Metropolitan Research Laboratory of Public Health. SO Int Conf AIDS. 1994 Aug 7-12;10(1):285 (abstract no. PC0061). Unique Identifier : AIDSLINE ICA10/94370055 AB OBJECTIVE: In order to elicit the seroprevalence of HIV in the people at the Tokyo district, we have been engaged in HIV antibody testing from 1987. METHODS: HIV antibody testing has been done for the persons who have visited health centers of Tokyo metropolitan district, using ELISA as the screening test, western blot and indirect immunofluorescent assay as the confirmation test. HIV-1 seropositive samples were tested for subtyping with V3 peptide ELISA. RESULTS: 193 HIV seropositive samples have been detected among 66731 samples that have been assayed since Feb. 1987 to Dec 1993. 113 seropositive samples and 72 ones were detected in 1992 and 1993 respectively. 152 samples out of seropositive ones were assayed to differentiate HIV-1 from HIV-2, and all were positive for HIV-1. In typing of V3 peptide ELISA, Euro-American type and Thai type has been predominant. DISCUSSION AND CONCLUSIONS: It is suggested that the infection rate of HIV-1 has been increased in a recent few years. HIV-2 infection has not yet prevailed among the people in Tokyo, we are going to the surveillance of HIV-2 as well as HIV-1. DE AIDS Serodiagnosis Human *HIV Seroprevalence *HIV-1 Tokyo/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).