Document 2556 DOCN M94A2556 TI The first decade of the AIDS epidemic among children in Brazil--a dynamic profile. DT 9412 AU Lauria L; Chequer P; Castilho E; Rodrigues L; Loures L; Ministry of Health, Brasilia, Brazil. SO Int Conf AIDS. 1994 Aug 7-12;10(1):277 (abstract no. PC0027). Unique Identifier : AIDSLINE ICA10/94370019 AB OBJECTIVE: To determine the changes in the profile of pediatric cases, within the first decade of the AIDS epidemic in Brazil. METHODS: All pediatric AIDS cases (< 15 yr.) reported to the Ministry of Health (MOH) from the beginning of the epidemic to 1993 were evaluated. RESULTS: While in 1985, 19 pediatric AIDS cases were registered, in 1993 120 cases were reported to the MOH. The largest increase was observed in children under 2: from 5 cases in 1985 (26%) to 141 in 1992 (52%). In the same period it was observed a reduction in the number of cases associated to reception of blood/components/hemophilia. On the other hand the number of cases resulting from mother to child transmission increased from 3 cases (16%) in 1985 to 219 (80%) in 1992. Since the beginning of the epidemic, pediatric AIDS cases have increased in all the Brazilian regions. However the proportional distribution did not change over the years. Most of the pediatric cases are still concentrated in the industrialized Southeast region. CONCLUSIONS: The pediatric AIDS epidemic in Brazil shifted to younger children over time. This shifting is related to the increment in HIV perinatal transmission as a result of the dissemination of the HIV/AIDS epidemic among women in childbearing age. DE Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION Brazil/EPIDEMIOLOGY Child Female Human Pregnancy Pregnancy Complications, Infectious MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).