Document 2560 DOCN M94A2560 TI IVDU is a key factor for changes in the AIDS epidemic in Brazil. DT 9412 AU Castilho E; Rodrigues I; Lauria I; Sereno A; Loures L; Ministry of Health, Brasilia, Brazil. SO Int Conf AIDS. 1994 Aug 7-12;10(1):276 (abstract no. PC0025). Unique Identifier : AIDSLINE ICA10/94370015 AB INTRODUCTION: A significant increase in the number of cases among women and adolescents is one of the changes that have been observed overtime in the epidemiological profile of the AIDS epidemic in Brazil. OBJECTIVE: To examine the factors involved in the increment of AIDS cases among women and adolescents in Brazil. METHODS: AIDS cases among women (> 15 years old) and adolescents (13-19) reported on a routine basis to the Ministry of Health were evaluated. RESULTS: Reported AIDS cases among Brazilian women increased from 13 (2.8%) in 1985 to 1525 (20.5%) in 1993. Of the total number of cases registered in 1993, 344 (22.5%) involved IVDU women and 438 (28.7%) were associated with heterosexual intercourse with IVDU; heterosexual intercourse with multiple partners accounted for 464 (30.4%) cases. Among adolescents, the number of cases increased from 16 in 1985 to 140 in 1993. This increment is largely associated with IVDU. In 1993, 45% of the total cases occurred in IVDUs. In parallel to the increment related to IVDU, heterosexual transmission increased when compared with homo/bisexual transmission. CONCLUSION: Prevention of the dissemination of the AIDS epidemic in Brazil must include aggressive strategies for reduction of the transmission associated with IVDU combined with strategies to control heterosexual transmission of HIV. DE Acquired Immunodeficiency Syndrome/*EPIDEMIOLOGY/TRANSMISSION Adolescence Brazil/EPIDEMIOLOGY Female Human Risk Factors Sex Behavior Substance Abuse, Intravenous/*COMPLICATIONS/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).