Document 2603
 DOCN  M94A2603
 TI    Clinical evaluation of different tests for Chlamydia
       trachomatis-infection.
 DT    9412
 AU    Petrova E; Borissov I; Dept. of Dermatology and Venerology High Medical
       School, Sofia,; Bulgaria.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):267 (abstract no. PB0497). Unique
       Identifier : AIDSLINE ICA10/94369972
 AB    OBJECTIVE: To compare results from three different tests detecting
       infection with Chlamydia trachomatis (Chl. tr.) and to evaluate them in
       respect to clinical diagnosis for genital-localized infection. MATERIAL
       AND METHODS: Serum samples from 368 patients attending STD and
       gynecological clinics were examined for presence of anti-Chl. tr.
       antibodies in Chlamydia-IgG-EIA (Labsystems, Finland), parallelly with
       two antigen-detecting assays: Chlamydia-Ag-EIA (Labsystems) and
       Clearview (Unipath, UK). All patients, positive in any test were treated
       and followed up for three to five months. RESULTS: Before and after
       treatment, results obtained in antigen-tests coincided and often were
       contraversial to that of antibody-detecting test. DISCUSSION: The
       serological testing for Chl. tr.-antibodies seems not conclusive for
       diagnosis of genital infection and effect of treatment. When a positive
       result for antibody is found, a thorough clinical examination and
       antigen-test should be performed.
 DE    Adult  Antibodies, Bacterial/BLOOD  Antigens, Bacterial/BLOOD
       *Chlamydia trachomatis/IMMUNOLOGY  Chlamydia
       Infections/*DIAGNOSIS/TRANSMISSION  Comparative Study  Female  Follow-Up
       Studies  Human  Male  Predictive Value of Tests  Sexually Transmitted
       Diseases, Bacterial/*DIAGNOSIS/TRANSMISSION  MEETING ABSTRACT

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