Document 2642 DOCN M94A2642 TI Oral pathology in pediatric patients with HIV infection. DT 9412 AU Sacco R; Startari R; Arosio A; Simoni L; Mannucci PM; Istituto Stomatologico Italiano, Milano. SO Int Conf AIDS. 1994 Aug 7-12;10(1):258 (abstract no. PB0460). Unique Identifier : AIDSLINE ICA10/94369933 AB OBJECTIVE: To determine type and frequency of oral pathology in pediatric patients with HIV infection and role in disease progression. METHODS: 53 pediatric patients with HIV infection were studied: 11 infants born from sexually infected mothers; 42 from drug abusers; median age was 5 years (range 7 month-10 years). 43 of these childrens were classified P 2 A stage and 10 AIDS stage. Oral hygiene, dental decay, periodontal condition, oral lesions, teeth development degree were evaluated. RESULTS: oral hygiene was similar to healthy subjects (plaque index 1.5)--all of 50 patients with teeth, showed dental enamel anomaly and 38 of them (75%) large enamel and dentine subjects. Herpes zoster was observed in five patients (10%); CMV was observed in one patient (2%) pseudomembranous candidiasis in eight patients (15%). Teeth development (permanent teeth) was greatly delayed. CONCLUSIONS: oral manifestations are common in pediatric patients with HIV infection and can be manageable. They were found to be possible markers and predictors of progression in HIV infection. In particular primary care of these patients should include use of sealants and flouride prophylaxis Although these manifestations can be tested, early prophylaxis is needed. DE AIDS-Related Opportunistic Infections/DIAGNOSIS/EPIDEMIOLOGY/ TRANSMISSION Child Child, Preschool *DMF Index Female Human HIV Infections/*DIAGNOSIS/EPIDEMIOLOGY/TRANSMISSION Infant Italy/EPIDEMIOLOGY Male Mouth Diseases/*DIAGNOSIS/EPIDEMIOLOGY *Oral Hygiene Index Tooth Abnormalities/*DIAGNOSIS/EPIDEMIOLOGY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).