Document 2658 DOCN M94A2658 TI Hematologic abnormalities in HIV nonvertically infected children. DT 9412 AU Strauss I; Marcu M; Marin C; Colentina Hospital, Bucharest, Romania. SO Int Conf AIDS. 1994 Aug 7-12;10(1):254 (abstract no. PB0444). Unique Identifier : AIDSLINE ICA10/94369917 AB OBJECTIVE: To compare hematologic abnormalities in HIV nonvertically infected children, a group who were not and a group who were cared for in a special AIDS hospital. METHODS: The first group of 88 children from orphanages were examined in autumn 1990, when first admitted in the Unit. The second group, examined in spring 1993 consisted of the 91 children cared for during more than 1 year in the Unit. Data also studied were: nutritional status, treatment (no zidovudine was given), stage of disease, social history. RESULTS: In first group, anemia (prevalence 75.8%) was 80.3% microcytic, 48.4% hypochromic. In second group, anemia (prevalence 80.2%) was 44.6% microcytic, 23.4% hypochromic. Leukocytes were higher than the normal average for the age groups in 70.4% of children of children in first group compared to 46.7% of those in second group. CONCLUSIONS: Improvement of nutritional status, prevention and management of secondary infections and also progression of disease modified the range of hematologic abnormalities. DE Acquired Immunodeficiency Syndrome/DIAGNOSIS/*IMMUNOLOGY Anemia/DIAGNOSIS/*IMMUNOLOGY Child Human HIV Seropositivity/DIAGNOSIS/*IMMUNOLOGY Institutionalization *Leukocyte Count Nutrition Assessment Romania MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).