Document 2784
 DOCN  M94A2784
 TI    Value of antioxidants & micronutrients in HIV/AIDS treatment.
 DT    9412
 AU    Ssali C; Mariandina AIDS Research Foundation, Uganda.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):225 (abstract no. PB0331). Unique
       Identifier : AIDSLINE ICA10/94369791
 AB    OBJECTIVES: To establish the value of a drug code-named Mariandina-A,
       containing antioxidants & micronutrients in the treatment of HIV/AIDS.
       METHODS: A cohort of 164 patients in stage 2 and 3 of WHO classification
       of HIV infection, rated between 40-70 by Karnofsky's Performance score
       had been treated over a period of 18 months were selected for a
       retrospective analysis using Karnofsky's performance score &
       haematology. RESULTS: Results of response after one complete year of
       treatment: TABULAR DATA, SEE ABSTRACT VOLUME. DISCUSSION AND CONCLUSION:
       The study indicates significant improvement in Karnofsky's performance
       score of over 40 points in 85.0% & CD4 counts rose by over 200/mm3 in
       53.0% cases while 33.3% deteriorated had less than 200/mm3 most of whom
       had Kaposi's Sarcoma & Tuberculosis. A double-blind placebo controlled
       study is underway.
 DE    Antioxidants/*THERAPEUTIC USE  Blood Sedimentation  Cohort Studies
       Double-Blind Method  Drug Combinations  Hemoglobins/ANALYSIS  Human  HIV
       Infections/BLOOD/*DRUG THERAPY  Karnofsky Performance Status  Leukocyte
       Count  Trace Elements/*THERAPEUTIC USE  Treatment Outcome  T4
       Lymphocytes  CLINICAL TRIAL  MEETING ABSTRACT  RANDOMIZED CONTROLLED
       TRIAL

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       protected by Copyright Law (Title 17, U.S.Code).