Document 2905
 DOCN  M94A2905
 TI    Ocular manifestations in HIV patients in Japan.
 DT    9412
 AU    Nagata Y; Fujino Y; Ono A; Mochizuki M; Oka S; Kimura S; Shimada K;
       Dept. of Ophthalmol., Univ. of Tokyo, Japan.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):198 (abstract no. PB0221). Unique
       Identifier : AIDSLINE ICA10/94369670
 AB    OBJECTIVE: Ocular disorders have been noted in patients infected with
       HIV and are one of the most serious complications in AIDS patients.
       However, the ocular features of HIV-seropositive patients have not been
       well documented in Japan, we investigated the ocular manifestations in
       70 HIV-seropositive patients. METHODS: Seventy HIV-seropositive patients
       (including 5 foreign patients) underwent ophthalmic examinations
       consisting of visual acuity testing, slit-lamp microscopy and indirect
       ophthalmoscopy between October 1989 and September 1992. Based on the
       cumulative totals, 25 of the cases had AIDS, 18 had ARC, and 36 were
       asymptomatic carriers (AC). RESULTS: Eighty percent of the AIDS cases
       had ocular manifestations, including cotton-wool spots (52%), retinal
       hemorrhages (56%), cytomegalovirus retinitis (40%) and pupil
       abnormalities (16%). The ocular signs were also seen in 72% of the ARC
       cases and 36% of the AC cases. DISCUSSION AND CONCLUSIONS: In Japanese
       HIV patients, it was appeared that ocular manifestations were also as
       common as in Western HIV patients. It is important to carry out a
       routine series of ophthalmic examinations for the early diagnosis and
       treatment.
 DE    Acquired Immunodeficiency Syndrome/COMPLICATIONS  AIDS-Related
       Complex/COMPLICATIONS  AIDS-Related Opportunistic
       Infections/EPIDEMIOLOGY/MICROBIOLOGY  Cytomegalovirus
       Retinitis/COMPLICATIONS/EPIDEMIOLOGY  Eye
       Diseases/COMPLICATIONS/*EPIDEMIOLOGY  Human  HIV
       Infections/*COMPLICATIONS  Japan/EPIDEMIOLOGY  Pupil  Retinal
       Hemorrhage/COMPLICATIONS/EPIDEMIOLOGY  Vitreous Body  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).