Document 2908
 DOCN  M94A2908
 TI    Risk factors for retinal detachment in patients with CMV-retinitis.
 DT    9412
 AU    Geier SA; Sadri I; Bogner JR; Klauss V; Goebel FD; Medizinische
       Poliklinik LMU, Munich, FRG.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):197 (abstract no. PB0218). Unique
       Identifier : AIDSLINE ICA10/94369667
 AB    OBJECTIVE: The purpose of this study was to investigate risk factors
       associated with retinal detachment in patients with AIDS and
       CMV-retinitis. PATIENTS AND METHODS: 69 patients with CMV-retinits were
       evaluated with respect to peripheral involvement of the retina. Myopia
       was evaluated as an additional not CMV-retinitis-related risk factor.
       RESULTS: Retinal detachment occurred in 12 patients (17%). In all 12
       patients (100%) with retinal detachment peripheral involvement (zone 3)
       was observed compared with 23 patients (40%) without retinal detachment.
       This accounts for a relative risk (RR) of 2.5 (p < 0.001). Myopia was
       observed in 10 patients (83%) with retinal detachment, and in 9 patients
       (16%) without retinal detachment. This accounts for a RR of 5.2 (p <
       0.001). A multivariate analysis demonstrated that zone 3 involvement
       remained a significant risk factor when controlling for myopia.
       CONCLUSION: Peripheral involvement and myopia are independent risk
       factors for the occurrence of retinal detachment. As
       pars-plana-vitrectomy with silicone-oil tamponade is successful in
       patients with AIDS a close monitoring is necessary in patients at risk
       for development of retinal detachment.
 DE    AIDS-Related Opportunistic Infections/*COMPLICATIONS  Cytomegalovirus
       Infections/COMPLICATIONS  Cytomegalovirus Retinitis/*COMPLICATIONS
       Human  Myopia/*COMPLICATIONS  Retinal Detachment/EPIDEMIOLOGY/*ETIOLOGY
       Risk Factors  Support, Non-U.S. Gov't  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).