Document 2967
 DOCN  M94A2967
 TI    Initial report of CD4 counts and oral lesions in a Texas HIV
       seropositive cohort.
 DT    9412
 AU    Yeh CK; Puttaiah R; Fabre C; Dove S; Cottone J; UTHSCSA, San Antonio
       78284-7919.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):184 (abstract no. PB0164). Unique
       Identifier : AIDSLINE ICA10/94369608
 AB    OBJECTIVE: A prospective surveillance program at an HIV/AIDS dedicated
       dental clinic has been developed to monitor HIV associated oral lesions
       in relationship to patients' general health. This is a preliminary
       report of the baseline data on disease characteristics of dental
       patients being treated at this clinic. METHODS: A computerized dental
       charting system was used which included information on socioeconomic and
       HIV status, dental and medical history, and a comprehensive oral
       examination with progress notes. Patients receiving dental service at
       the Sansing Dental Clinic, Austin, Texas, were enrolled in this program.
       RESULTS: Two hundred forty-eight patient charts were reviewed and
       frequency distributions calculated for program variables. Ninety-two
       percent were male and 8% female. The mean age was 35 (SD = 7) years, and
       majority were non-Hispanic White (61%). Forty-four percent had medical
       insurance with only 16% having dental insurance. The mean CD4 count was
       262 (SD = 214) and 46.4% having < 200. Approximately 61% took one or
       more anti-HIV medications. A total of 171 HIV-related soft tissue oral
       lesions (hairy leukoplakia, candidiasis or Kaposi's Sarcoma) and 26
       HIV-associated periodontal disease were found. A negative association
       between CD4 counts and the number of HIV oral manifestations (R2 =
       0.079, p = 0.0001) was noted. In addition, 81 reported xerostomia and 51
       reported taste changes. DMFT was 11.2 (SD = 6.2). DISCUSSION AND
       CONCLUSIONS: Our data indicates an inverse relationship between the CD4
       counts and oral lesions. The computerized surveillance program could be
       applied to multiple dental clinic sites to monitor oral health needs,
       and to study the impact of oral lesions associated with the progression
       of HIV infection.
 DE    Adult  AIDS-Related Opportunistic Infections/*IMMUNOLOGY  Candidiasis,
       Oral/IMMUNOLOGY  Female  Human  HIV Seropositivity/*IMMUNOLOGY
       Leukocyte Count  Leukoplakia, Oral/IMMUNOLOGY  Male  Middle Age  Mouth
       Diseases/*IMMUNOLOGY  Mouth Neoplasms/*IMMUNOLOGY  Texas  T4
       Lymphocytes/*IMMUNOLOGY  MEETING ABSTRACT

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).