Document 2994
 DOCN  M94A2994
 TI    A case of HIV positive hemophilia a with hepatocellular carcinoma.
 DT    9412
 AU    Tao M; Karino Y; Yoshida J; Kobayashi S; Hashino S; Imamura M; Sakurada
       K; Miyazaki T; 3rd Dept. of Int. Med., Hokkaido Univ. Sch. Med.,
       Sapporo, Japan.
 SO    Int Conf AIDS. 1994 Aug 7-12;10(1):178 (abstract no. PB0140). Unique
       Identifier : AIDSLINE ICA10/94369581
 AB    OBJECTIVE: Double infection with HIV and HCV is commonly observed in
       hemophilia patients. Nevertheles, there are a few reports on the
       development of hepatocellular carcinoma (HCC) in these patients. We
       analyzed correlation between HIV infection and the development of HCC
       due to HCV infection. RESULTS: HCC developed in a 53-year-old male
       patient infected with HIV and HCV. He had liver dysfunction at 39 years
       old and diagnosed as non A non B hepatitis. Finally, it turned out that
       this liver dysfunction was due to HCV. Furthermore, HIV infection was
       found at 47 years old and now he is in the stage of CDC IV class.
       Although transcatheter arterial infusion (TAI) using lipiodol and
       epirubicin once reduced the primary tumor mass, another tumor developed
       4 months later. CONCLUSIONS: Immunodeficiency due to HIV infection did
       not appear to shorten the time of HCC development, showing a natural
       course. In a clinical sence, precise examinations are required to find
       out the development of HCC at the initial stage.
 DE    Carcinoma, Hepatocellular/*DIAGNOSIS  Case Report  Follow-Up Studies
       Hemophilia/*COMPLICATIONS  Hepatitis C/*DIAGNOSIS/TRANSMISSION  Human
       HIV Seropositivity/*DIAGNOSIS/TRANSMISSION  Liver Neoplasms/*DIAGNOSIS
       Male  Middle Age  Neoplasm Recurrence, Local/DIAGNOSIS  MEETING ABSTRACT

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