Document 0113
 DOCN  M9550113
 TI    Neuropsychological performance and CD4 levels in HIV-1 asymptomatic
       infection.
 DT    9505
 AU    Podraza AM; Bornstein RA; Whitacre CC; Para MF; Fass RJ; Rice RR Jr;
       Nasrallah HA; Maine Head Trauma Center Bangor.
 SO    J Clin Exp Neuropsychol. 1994 Oct;16(5):777-83. Unique Identifier :
       AIDSLINE MED/95138241
 AB    The performance of 68 HIV-1 seropositive asymptomatic (HIV+) subjects
       stratified on CD4 levels were compared with 82 HIV-1 seronegative (HIV-)
       subjects on a battery of neuropsychological, mood state, and perceived
       health status measures. The neuropsychological test battery included
       measures of attention, reaction time, memory, intellectual ability,
       psychomotor speed, frontal lobe or executive function, and decision
       time. None of the HIV+ subjects were taking antiviral agents. The groups
       did not differ for age, mood state, or WAIS-R Verbal and Performance IQ
       scores. Due to group differences for education and weekly ethanol
       consumption, both variables were used as covariates in multivariate
       analyses of variance. Relatively few differences were observed between
       subgroups of HIV+ patients or between these subgroups and control
       subjects. These data suggest that factors other than absolute levels of
       immunosuppression as expressed by CD4 levels alone, appear to be
       responsible for the deficits observed in HIV+ asymptomatic patients.
 DE    Adult  AIDS Dementia Complex/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY  *CD4
       Lymphocyte Count  Frontal Lobe/PHYSIOPATHOLOGY  Human  HIV
       Seronegativity  HIV Seropositivity/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY
       HIV-1/*IMMUNOLOGY  Longitudinal Studies  Male  Middle Age
       *Neuropsychological Tests/STATISTICS & NUMER DATA  Psychometrics
       Reference Values  Support, U.S. Gov't, P.H.S.  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).