Document 0345 DOCN M9550345 TI Efficacy of oral amphotericin B in AIDS patients with thrush clinically resistant to fluconazole. DT 9505 AU Dewsnup DH; Stevens DA; Department of Medicine, Santa Clara Valley Medical Center, San; Jose, California 95128-2699. SO J Med Vet Mycol. 1994;32(5):389-93. Unique Identifier : AIDSLINE MED/95147151 AB Reports of thrush clinically refractory to azoles in AIDS patients are increasing with the more widespread use of these agents. We studied our own oral preparation of amphotericin B in the treatment of two AIDS patients who developed oral thrush due to Candida glabrata after prolonged fluconazole use. Improvement occurred in both in less than 1 week, with eventual clearing and absence of side effects. Oral amphotericin B may have advantages over alternatives for this increasing problem. DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS Administration, Oral Adult Amphotericin B/*ADMINISTRATION & DOSAGE Candidiasis, Oral/COMPLICATIONS/*DRUG THERAPY Case Report Cost-Benefit Analysis Drug Resistance, Microbial Fluconazole/*THERAPEUTIC USE Human Male Treatment Outcome JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).