Document 0413
 DOCN  M9550413
 TI    Bone scintigraphy as a prognostic factor in patients with adult T-cell
       leukemia-lymphoma.
 DT    9505
 AU    Hoshi H; Nagamachi S; Jinnouchi S; Ohnishi T; Shigemi F; Watanabe K;
       Department of Radiology, Miyazaki Medical College, Japan.
 SO    Clin Nucl Med. 1994 Nov;19(11):992-5. Unique Identifier : AIDSLINE
       MED/95144869
 AB    Bone scintigraphy in 26 patients with adult T-cell leukemia-lymphoma
       (ATLL) was evaluated. Abnormally high accumulations were observed in 7
       of 26 patients (skull, 5; vertebra, 1; rib, 6; bony pelvis, 1; scapula,
       2; lower extremities, 1). Serum calcium levels were significantly
       elevated in patients with abnormally high accumulations on bone
       scintigraphy. Survival rates of the patients with positive results on
       bone scintigraphy were significantly lower than were those with negative
       results on bone scintigraphy (P < 0.05). Survival rates of patients with
       high serum calcium levels, high WBC counts, and high serum lactate
       dehydrogenase (LDH) levels were also significantly lower than were those
       of the negative groups, in this order of significance. Bone scintigraphy
       was useful for detecting bone marrow involvement in ATLL and it can be
       one of the better indicators of the prognoses of patients with ATLL.
 DE    Bone and Bones/*RADIONUCLIDE IMAGING  Calcium/BLOOD  Female  Human
       Lactate Dehydrogenase/BLOOD  Leukemia-Lymphoma, T-Cell, Acute,
       HTLV-I-Associated/BLOOD/  *MORTALITY/*RADIONUCLIDE IMAGING  Leukocyte
       Count  Male  Middle Age  Prognosis  Survival Rate  Technetium Tc 99m
       Medronate/*DIAGNOSTIC USE  JOURNAL ARTICLE

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