Document 0437
 DOCN  M9550437
 TI    Ferritin levels in pediatric HIV-1 infection.
 DT    9505
 AU    Ellaurie M; Rubinstein A; George Washington University School of
       Medicine, Washington, DC.
 SO    Acta Paediatr. 1994 Oct;83(10):1035-7. Unique Identifier : AIDSLINE
       MED/95143842
 AB    Ferritin is an acute phase protein which is often elevated in acute and
       chronic inflammation, as well as in neoplastic disease. In adults with
       human immunodeficiency virus (HIV) infection, elevated serum ferritin
       levels indicate advanced or progressive disease. In the present study,
       ferritin levels were evaluated in 88 HIV-infected children. Ferritin
       levels greater than 100 ng/ml were found in 93% of patients with
       advanced disease. Increasing levels always accompanied or closely
       preceded rapid disease progression. Serum ferritin levels may prove to
       be a useful marker to monitor disease progression and therapeutic
       efficacy in HIV-infected children.
 DE    AIDS-Related Opportunistic Infections/BLOOD  Biological Markers/BLOOD
       Child  Child, Preschool  Disease Progression  Ferritin/*BLOOD  Human
       HIV Infections/*BLOOD  *HIV-1  Infant  JOURNAL ARTICLE

       SOURCE: National Library of Medicine.  NOTICE: This material may be
       protected by Copyright Law (Title 17, U.S.Code).