Document 0453 DOCN M9550453 TI Comparative analysis of HIV-1 and HIV-2 indeterminate western blot patterns. DT 9505 AU Ayisi NK; Aidoo M; Virology Unit, Noguchi Memorial Institute for Medical Research,; University of Ghana, Legon. SO West Afr J Med. 1994 Jul-Sep;13(3):164-7. Unique Identifier : AIDSLINE MED/95143180 AB A comparison of HIV-1 and HIV-2 indeterminate Western blot patterns of Ghanaian sera collected between 1989 and 1990 was made. Antibodies to group specific antigen (GAG) gene products were most frequently detected both HIV-1 and HIV-2 indeterminate sera. HIV-2 GAG gene product p26 was shown to be a non-specific indicator of infection. Antibody to gp120, and envelope gene product of HIV-1 never occurred in indeterminate sera whereas antibodies to all the envelope gene products of HIV-2 were detected in indeterminate sera. DE Blotting, Western/METHODS Comparative Study Enzyme-Linked Immunosorbent Assay Ghana/EPIDEMIOLOGY Human HIV Antibodies/*BLOOD HIV Envelope Protein gp120/IMMUNOLOGY HIV Seropositivity/EPIDEMIOLOGY/*IMMUNOLOGY *HIV-1/IMMUNOLOGY *HIV-2/IMMUNOLOGY Population Surveillance Seroepidemiologic Methods Support, Non-U.S. Gov't JOURNAL ARTICLE SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).